| ncRNA name | tau siRNA |
| ncRNA Category | siRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Mus musculus |
| Tissues/Cell_line | retinas |
| Methods | siRNA injection, PERG, VEP, immunohistochemistry, TUENL assay, Western blot |
| Expression pattern | associated |
| Functional description | Intravitreal administration of an siRNA targeting to tau or a specific inhibitor of GSK3β reverses synapse loss and restores visual function of RGCs by attenuating tau hyperphosphorylation within a certain time frame of DR. |
| PubMed ID | 30466464 |
| Year | 2018 |
| Title | GSK3β-mediated tau hyperphosphorylation triggers diabetic retinal neurodegeneration by disrupting synaptic and mitochondrial functions. |
| Drug-related ncRNA | NO |
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